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The benefits of exercise range from prevention of cachexia -severe loss of weight and muscle mass - and control of arterial blood pressure to improved cardiac function, postponing a degenerative process that causes progressive heart cell death. About 70% of heart failure patients die from the condition within five years. A study by the University of São Paulo (USP) in Brazil, published recently in the journal  Autophagy , helps to elucidate part of the mechanism whereby aerobic exercise protects the sick heart. "Basically, we discovered that aerobic training facilitates the removal of dysfunctional mitochondria from heart cells," said Julio Cesar Batista Ferreira, a professor at the Biomedical Science Institute (ICB-USP) and principal investigator for the project which was supported by the São Paulo Research Foundation (FAPESP) Mitochondria are the organelles in charge of providing energy to cells. "The removal of dysfunctional mitochondria increases the supply o...

A three-dimensional magnetic resonance picture type a affected person who has undergone an acute myocardial infarction. The guts is seen within the heart of the picture. Wholesome (non-infarcted) cardiac muscle is indicated by asterisks, whereas arrows level to the infarcted area. MRI can reveal the extent of the realm affected by irritation after a coronary heart assault (the yellow infarcted area marked by arrows). Serial MRI research reveal that this inflammatory response seems instantly after the infarction however then quickly resolves after which reappears a number of days after the infarction. Credit score: CNIC Scientists on the Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC) and the Fundación Jiménez Díaz (FJD) and Salamanca College Hospitals have demonstrated that the response of the human coronary heart to an infarction could be very totally different to what was beforehand thought. The research, led by heart specialist Borja Ibáñez and ...