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It's already known some fish have big hearts -- at least during the winter. Now a U of G professor has identified a protein that enables fish to change the size of their hearts based on the temperature of the water. The finding might yield clues to treating or preventing heart damage in humans. "Fish put on collagen in the winter and take it off in the summer," said Todd Gillis, whose study, conducted with PhD student Elizabeth Johnston, was recently published in the  Journal of Experimental Biology . "They do this so they can keep swimming over a broad range of temperatures." Understanding how fish are able to add and remove collagen is important because fish hearts and human hearts are similar in composition, said Gillis, a professor in the Department of Integrative Biology. When our heart becomes injured from a heart attack or other stressor, the body responds by building a scar, composed of collagen, in the damaged area. This scar is permanent ...

The cardiac intensive care unit is no longer only a place for patients recovering from heart attacks, like the coronary care units of decades past. A new University of Michigan study finds slightly more than half of heart patients are admitted to the CICU for noncardiac conditions, such as sepsis or renal failure, rather than for a heart condition. "It's an opportunity for providers to assess training and staffing models," says lead author Shashank S. Sinha, M.D., M.Sc., an advanced heart failure and cardiac transplantation fellow at U-M's Frankel Cardiovascular Center. The study was recently published in  Circulation: Cardiovascular Quality and Outcomes . "In order to get admitted to a CICU, you either have a primary cardiac condition -- such as a heart attack or heart failure -- or you have a sick heart from a prior event and now are admitted with a primary noncardiac condition -- such as sepsis or lung or kidney failure," Sinha says. "We fou...

Smoking increases the risk of developing a number of diseases , such as chronic obstructive pulmonary disease (COPD), coronary heart disease, stroke and peripheral vascular disease, all of which can potentially have negative effects on people's physical, psychological and social health. Frailty is considered a precursor to, but a distinct state from, disability. Frailty is a condition associated with decreased physiological reserve and increased vulnerability to adverse health outcomes. The outcomes include falls, fractures, disability, hospitalisation and institutionalisation. Frailty has also been shown to be linked to worse psychological or cognitive outcomes, such as poor quality of life and dementia. Due to the potential for reversibility of frailty, identifying potentially modifiable risk factors of frailty may help to develop strategies to prevent or slow progression of adverse health outcomes associated with both frailty and smoking. Researchers here aimed to exami...

The research published today in the  American Journal of Public Health , calculated years of life lost to the top 15 causes of death in the United States between 1995 and 2015 (examining more than 2 million death certificates each year), compared it to the number of deaths and examined reasons for differences. "Focusing on life-years provides perspective on the societal burden of disease and highlights the disparities in disease burden," said Glen Taksler, Ph.D., Cleveland Clinic researcher and lead author of the study. "Reordering mortality by life-years lost paints a more complete picture of changing mortality and its distribution across various populations." As an example, researchers concluded that, although heart disease is the leading cause-of-death overall, other conditions, such as cancer, caused more life-years lost. In 2015, heart disease caused 6 percent more deaths than cancer -- 635,310 compared to 596,730 -- but cancer caused 23 percent more l...

The protruding elements seen in the different slides are cholesterol crystals. Those elements are arising from within the artery wall, causing tearing and damage to the artery. The colors have been added for enhancement and imagery. Credit: Michigan State University A new Michigan State University study on 240 emergency room patients shows just how much of a role a person's cholesterol plays, when in a crystallized state , during a heart attack. George Abela, lead author and chief cardiologist at MSU, analyzed the material that was obstructing the coronary arteries of patients who had suffered a heart attack and found that 89 percent of them had an excessive amount of these crystallized structures, referred to as cholesterol crystals. The research is now published online in the  American Journal of Cardiology . These crystals are released from plaque that can build up in the heart and is often made up of fat, calcium and other substances as well. When this mat...

Among 146,748 women with a first pregnancy and a follow-up of approximately four-and-a-half years , 997 were diagnosed with cardiovascular disease and 6812 developed hypertension. Compared with women without hypertension during pregnancy, those with hypertension during pregnancy had a 2.2-times higher risk of developing cardiovascular disease and a 5.6-times higher risk of developing hypertension after pregnancy. Subsequent pregnancies did not appear to influence these associations. "This study highlights the need for long-term follow-up of women with a history of hypertension during pregnancy to provide early management of risk factors for cardiovascular disease," said Sonia Grandi, PhD candidate at McGill University and lead author of the  Paediatric & Perinatal Epidemiology  study. for more information visit our product website:   Buy Tadarise Pro 40mg Online